Preferred Name

Nitric Oxide [Chemical/Ingredient]

Synonyms

Nitric Oxide

ID

http://purl.bioontology.org/ontology/NDFRT/N0000006603

altLabel

Nitric Oxide

Nitrogen Monoxide

Endogenous Nitrate Vasodilator

Nitrogen oxide (NO)

Mononitrogen Monoxide

Nitric Oxide, Endothelium-Derived

cui

C0028128

Ingredient of

http://purl.bioontology.org/ontology/NDFRT/N0000178214

http://purl.bioontology.org/ontology/NDFRT/N0000148689

MESH DEFINITION

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.

MESH DUI

D009569

MeSH name

Nitric Oxide

MESH UI

M0014877

NDFRT kind

INGREDIENT_KIND

notation

N0000006603

NUI

N0000006603

prefLabel

Nitric Oxide [Chemical/Ingredient]

tui

T197

T121

T123

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000011364

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