Preferred Name |
Receptor, Insulin [Chemical/Ingredient] |
|
Synonyms |
Receptors, Insulin Insulin Receptor Insulin Receptor Protein-Tyrosine Kinase Insulin-Dependent Tyrosine Protein Kinase Receptor, Insulin |
|
ID |
http://purl.bioontology.org/ontology/NDFRT/N0000168857 |
|
altLabel |
Receptors, Insulin Insulin Receptor Insulin Receptor Protein-Tyrosine Kinase Insulin-Dependent Tyrosine Protein Kinase Receptor, Insulin |
|
cui |
C0034818 |
|
MESH DEFINITION |
A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE. |
|
MESH DUI |
D011972 |
|
MeSH name |
Receptor, Insulin |
|
MESH UI |
M0018605 |
|
NDFRT kind |
INGREDIENT_KIND |
|
notation |
N0000168857 |
|
NUI |
N0000168857 |
|
prefLabel |
Receptor, Insulin [Chemical/Ingredient] |
|
tui |
T116 T126 T192 |
|
subClassOf |