Preferred Name

Receptor, Insulin [Chemical/Ingredient]

Synonyms

Receptors, Insulin

Insulin Receptor

Insulin Receptor Protein-Tyrosine Kinase

Insulin-Dependent Tyrosine Protein Kinase

Receptor, Insulin

ID

http://purl.bioontology.org/ontology/NDFRT/N0000168857

altLabel

Receptors, Insulin

Insulin Receptor

Insulin Receptor Protein-Tyrosine Kinase

Insulin-Dependent Tyrosine Protein Kinase

Receptor, Insulin

cui

C0034818

MESH DEFINITION

A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.

MESH DUI

D011972

MeSH name

Receptor, Insulin

MESH UI

M0018605

NDFRT kind

INGREDIENT_KIND

notation

N0000168857

NUI

N0000168857

prefLabel

Receptor, Insulin [Chemical/Ingredient]

tui

T116

T126

T192

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000168795

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