Preferred Name

DNA Topoisomerases, Type I [Chemical/Ingredient]

Synonyms

DNA Untwisting Protein

ID

http://purl.bioontology.org/ontology/NDFRT/N0000168111

altLabel

DNA Untwisting Protein

Topoisomerase I

DNA Untwisting Enzyme

DNA topoisomerase

DNA Topoisomerases, Type I

DNA Relaxing Protein

DNA Untwisting Enzymes

DNA Nicking-Closing Proteins

DNA Topoisomerase

Type I DNA Topoisomerase

DNA Relaxing Enzyme

DNA Untwisting Proteins

DNA Relaxing Enzymes

DNA Nicking-Closing Protein

DNA Topoisomerase I

DNA Type 1 Topoisomerase

cui

C0012920

MESH DEFINITION

DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix.

MESH DUI

D004264

MeSH name

DNA Topoisomerases, Type I

MESH UI

M0381011

NDFRT kind

INGREDIENT_KIND

notation

N0000168111

NUI

N0000168111

prefLabel

DNA Topoisomerases, Type I [Chemical/Ingredient]

tui

T116

T126

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000168104

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