loading...| Preferred Name |
Aprotinin [Chemical/Ingredient] |
|
| Synonyms |
Bovine Pancreatic Trypsin Inhibitor |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000007185 |
|
| altLabel |
Bovine Pancreatic Trypsin Inhibitor Kallikrein-Trypsin Inactivator Kunitz Pancreatic Trypsin Inhibitor Trypsin Inhibitor, Basic, Pancreatic Bovine Kunitz Pancreatic Trypsin Inhibitor Aprotinin Trypsin Inhibitor, Kunitz, Pancreatic Basic Pancreatic Trypsin Inhibitor BPTI, Basic Pancreatic Trypsin Inhibitor |
|
| cui |
C0003641 |
|
| Ingredient of | ||
| MESH DEFINITION |
A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995) |
|
| MESH DUI |
D007611 |
|
| MeSH name |
Aprotinin |
|
| MESH UI |
M0011905 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000007185 |
|
| NUI |
N0000007185 |
|
| prefLabel |
Aprotinin [Chemical/Ingredient] |
|
| tui |
T116 T123 T121 |
|
| subClassOf |