loading...| Preferred Name |
Sirolimus [Chemical/Ingredient] |
|
| Synonyms |
Rapamycin Sirolimus |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000006605 |
|
| altLabel |
Rapamycin Sirolimus |
|
| Contraindicating class of |
http://purl.bioontology.org/ontology/NDFRT/N0000163931 http://purl.bioontology.org/ontology/NDFRT/N0000163932 http://purl.bioontology.org/ontology/NDFRT/N0000163934 |
|
| cui |
C0072980 |
|
| Ingredient of |
http://purl.bioontology.org/ontology/NDFRT/N0000181517 http://purl.bioontology.org/ontology/NDFRT/N0000148624 http://purl.bioontology.org/ontology/NDFRT/N0000164317 http://purl.bioontology.org/ontology/NDFRT/N0000181516 |
|
| MESH DEFINITION |
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties. |
|
| MESH DUI |
D020123 |
|
| MeSH name |
Sirolimus |
|
| MESH UI |
M0029863 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000006605 |
|
| NUI |
N0000006605 |
|
| prefLabel |
Sirolimus [Chemical/Ingredient] |
|
| tui |
T109 T195 |
|
| subClassOf |