loading...| Preferred Name |
Nucleoside Reverse Transcriptase Inhibitor |
|
| Synonyms |
Nucleoside Analog Reverse Transcriptase Inhibitor Nucleoside Reverse Transcriptase Inhibitor NRTI |
|
| Definitions |
A substance with a structure similar to a nucleoside molecule that is capable of occupying the active catalytic site of a reverse transcriptase resulting in inhibition of enzyme function, chain termination, and inhibition of viral replication. These compounds are converted to their active phosphorylated forms by cellular kinases. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97452 |
|
| code |
C97452 |
|
| DEFINITION |
A substance with a structure similar to a nucleoside molecule that is capable of occupying the active catalytic site of a reverse transcriptase resulting in inhibition of enzyme function, chain termination, and inhibition of viral replication. These compounds are converted to their active phosphorylated forms by cellular kinases. |
|
| FULL_SYN |
Nucleoside Analog Reverse Transcriptase Inhibitor Nucleoside Reverse Transcriptase Inhibitor NRTI |
|
| label |
Nucleoside Reverse Transcriptase Inhibitor |
|
| Preferred_Name |
Nucleoside Reverse Transcriptase Inhibitor |
|
| prefixIRI |
Thesaurus:C97452 |
|
| Semantic_Type |
Chemical Viewed Functionally |
|
| UMLS_CUI |
C1373111 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/NCIT_C97452 | BERO | LOOM | |
| http://scai.fraunhofer.de/HuPSON#SCAIVPH_00001109 | HUPSON | LOOM | |
| http://purl.jp/bio/4/id/201106036854521097 | IOBC | LOOM |