National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Edoxaban

Synonyms

N-(5-chloropyridin-2-yl)-N'-[(1S,2R,4S)-4-(N,N-dimethylcarbamoyl)-2-(5-methyl-4,5,6,7- tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl]oxamide

Ethanediamide, n1-(5-chloro-2-pyridinyl)-n2-((1s,2r,4s)-4- ((dimethylamino)carbonyl)- 2-(((4,5,6,7-tetrahydro-5-methylthiazolo(5,4-c)pyridin-2-yl)carbonyl)amino)cyclohexyl)-

DU-176

EDOXABAN

Edoxaban

Definitions

An orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Edoxaban is administered as edoxaban tosylate. This agent has an elimination half-life of 9-11 hours and undergoes renal excretion.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96539

CAS_Registry

480449-70-5

Chemical_Formula

C24H30ClN7O4S

code

C96539

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

HemOnc

DEFINITION

An orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Edoxaban is administered as edoxaban tosylate. This agent has an elimination half-life of 9-11 hours and undergoes renal excretion.

Display_Name

Edoxaban

FDA_UNII_Code

NDU3J18APO

FULL_SYN

N-(5-chloropyridin-2-yl)-N'-[(1S,2R,4S)-4-(N,N-dimethylcarbamoyl)-2-(5-methyl-4,5,6,7- tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl]oxamide

Ethanediamide, n1-(5-chloro-2-pyridinyl)-n2-((1s,2r,4s)-4- ((dimethylamino)carbonyl)- 2-(((4,5,6,7-tetrahydro-5-methylthiazolo(5,4-c)pyridin-2-yl)carbonyl)amino)cyclohexyl)-

DU-176

EDOXABAN

Edoxaban

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96542

label

Edoxaban

Preferred_Name

Edoxaban

prefixIRI

Thesaurus:C96539

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C2975435

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173067

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180619

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/LNC/LP220255-6 LOINC LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571352688529240133 ACVD_ONTOLOGY LOOM
http://www.semanticweb.org/maria/ontologies/2023/1/OntologiaByMAF#OWLClass_abf59932_96cc_4204_a99a_2feb224dce18 SP_ONTOLOGY LOOM
http://purl.bioontology.org/ontology/LNC/LA28657-7 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C552171 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/B01AF03 ATC LOOM
https://go.drugbank.com/drugs/DB09075 MDM LOOM
http://purl.obolibrary.org/obo/CHEBI_85973 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_85973 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_85973 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_85973 DRON LOOM
http://purl.bioontology.org/ontology/VANDF/4034081 VANDF LOOM
http://purl.jp/bio/4/id/201106045041035119 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/015852 NDDF LOOM
http://purl.obolibrary.org/obo/NCIT_C96539 BERO LOOM
http://purl.bioontology.org/ontology/RXNORM/1599538 RXNORM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/712778008 SNOMEDCT LOOM
http://stirdf.jst.go.jp/id/201007083102189373 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU054567 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000191384 NDFRT LOOM
http://purl.bioontology.org/ontology/MESH/C552171 MESH LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_d954c6ec_2f38_498c_a19f_cd5ffb6c461b STO-DRAFT LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_d954c6ec_2f38_498c_a19f_cd5ffb6c461b CVAO LOOM
http://bmi.utah.edu/ontologies/peontology/C2975435 PE LOOM
http://purl.obolibrary.org/obo/CHEBI_85973 CHEBI LOOM