National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Selective Serotonin Reuptake Inhibitor

Synonyms

Selective Serotonin Reuptake Inhibitor

selective serotonin reuptake inhibitor

SSRI

Definitions

Any agent that increases the extracellular level of the neurotransmitter serotonin (5-HT) by inhibiting its reuptake into the presynaptic cell. Increased level in the synaptic cleft prolongs the action of 5-HT on the postsynaptic receptor. This type of agent is typically used as an antidepressant and in the treatment of anxiety disorders and some personality disorders. They are also typically effective and used in treating some cases of insomnia.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C94725

ALT_DEFINITION

A type of drug that is used to treat depression. Selective serotonin reuptake inhibitors slow the process by which serotonin (a substance that nerves use to send messages to one another) is reused by nerve cells that make it. This increases the amount of serotonin available for stimulating other nerves.

CHEBI_ID

CHEBI:50949

code

C94725

DEFINITION

Any agent that increases the extracellular level of the neurotransmitter serotonin (5-HT) by inhibiting its reuptake into the presynaptic cell. Increased level in the synaptic cleft prolongs the action of 5-HT on the postsynaptic receptor. This type of agent is typically used as an antidepressant and in the treatment of anxiety disorders and some personality disorders. They are also typically effective and used in treating some cases of insomnia.

FULL_SYN

Selective Serotonin Reuptake Inhibitor

selective serotonin reuptake inhibitor

SSRI

label

Selective Serotonin Reuptake Inhibitor

Preferred_Name

Selective Serotonin Reuptake Inhibitor

prefixIRI

Thesaurus:C94725

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0360105

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78272

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