National Cancer Institute Thesaurus

Last uploaded: August 27, 2019
Preferred Name

Dronabinol

Synonyms

Delta-9-Tetrahydrocannabinol

DRONABINOL

Delta(9)-Tetrahydrocannibinol

Delta 9-Tetrahydrocannabinol

THC

Marinol

Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol

SP-104

(-)-.DELTA.9-Tetrahydrocannabinol

SP 104

Abbott 40566

Tetrahydrocannabinol

Dronabinol

SYNDROS

Delta9-THC

Delta-9-THC

dronabinol

Definitions

An isomer of tetrahydrocannabinol (THC) that is the main and most active isomer found in the Cannabis sativa L. plant, with potential anti-emetic, analgesic and appetite stimulating activities. Upon administration, dronabinol, also called delta-9-THC, targets and binds to cannabinoid receptors (CBRs) located in the central nervous system (CNS). Dronabinol acts directly on the appetite and vomiting control centers in the brain to stimulate appetite and prevent emesis. In addition, this agent induces analgesia. Urine levels may be used as a marker to determine the exposure to certain preparations containing parts of the cannabis plant, such as marijuana.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C867

ALT_DEFINITION

A synthetic pill form of delta-9-tetrahydrocannabinol (THC), an active ingredient in marijuana that is used to treat nausea and vomiting associated with cancer chemotherapy.

CAS_Registry

1972-08-3

Chemical_Formula

C21H30O2

code

C867

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

Contributing_Source

CTRP

FDA

DEFINITION

An isomer of tetrahydrocannabinol (THC) that is the main and most active isomer found in the Cannabis sativa L. plant, with potential anti-emetic, analgesic and appetite stimulating activities. Upon administration, dronabinol, also called delta-9-THC, targets and binds to cannabinoid receptors (CBRs) located in the central nervous system (CNS). Dronabinol acts directly on the appetite and vomiting control centers in the brain to stimulate appetite and prevent emesis. In addition, this agent induces analgesia. Urine levels may be used as a marker to determine the exposure to certain preparations containing parts of the cannabis plant, such as marijuana.

Display_Name

Dronabinol

FDA_UNII_Code

7J8897W37S

FULL_SYN

Delta-9-Tetrahydrocannabinol

DRONABINOL

Delta(9)-Tetrahydrocannibinol

Delta 9-Tetrahydrocannabinol

THC

Marinol

Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol

SP-104

(-)-.DELTA.9-Tetrahydrocannabinol

SP 104

Abbott 40566

Tetrahydrocannabinol

Dronabinol

SYNDROS

Delta9-THC

Delta-9-THC

dronabinol

label

Dronabinol

Legacy_Concept_Name

Dronabinol

NSC_Code

134454

PDQ_Closed_Trial_Search_ID

39707

PDQ_Open_Trial_Search_ID

39707

Preferred_Name

Dronabinol

prefixIRI

ncit:C867

Semantic_Type

Pharmacologic Substance

Organic Chemical

UMLS_CUI

C0039663

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C267

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http://purl.bioontology.org/ontology/NDFRT/N0000146833 NDFRT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386846008 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MESH/D013759 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013759 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/001685 NDDF LOOM
http://purl.bioontology.org/ontology/UATC/A04AD10 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4018511 VANDF LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039707 PDQ LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.849.090.810 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB00470 FTC LOOM