National Cancer Institute Thesaurus

Last uploaded: October 30, 2018
Preferred Name

Riboflavin

Synonyms

Riboflavin

Vitamin B2

Lactoflavin

riboflavin

6,7-Dimethyl-9-D-ribitylisoalloxazine

RIBOFLAVIN

vitamin B2

Riboflavine

Definitions

An essential human nutrient that is a heat-stable and water-soluble flavin belonging to the vitamin B family. Riboflavin is a precursor of the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). These coenzymes are of vital importance in normal tissue respiration, pyridoxine activation, tryptophan to niacin conversion, fat, carbohydrate, and protein metabolism, and glutathione reductase mediated detoxification. Riboflavin may also be involved in maintaining erythrocyte integrity. This vitamin is essential for healthy skin, nails, and hair.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C808

ALT_DEFINITION

Water-soluble vitamin that is a coenzyme in numerous oxidation-reduction reactions. (DRI)

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Riboflavin helps make red blood cells, helps some enzymes work properly, and keeps skin, nails, and hair healthy. It is found in milk, eggs, malted barley, organ meats, yeast, and leafy vegetables. Riboflavin is water-soluble (can dissolve in water) and must be taken in every day. Not enough riboflavin can cause anemia (a low number of red blood cells), mouth sores, and skin problems. Amounts of riboflavin may be higher in the blood of patients with some types of cancer.

CAS_Registry

83-88-5

CHEBI_ID

CHEBI:17015

Chemical_Formula

C17H20N4O6

code

C808

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

FDA

DEFINITION

An essential human nutrient that is a heat-stable and water-soluble flavin belonging to the vitamin B family. Riboflavin is a precursor of the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). These coenzymes are of vital importance in normal tissue respiration, pyridoxine activation, tryptophan to niacin conversion, fat, carbohydrate, and protein metabolism, and glutathione reductase mediated detoxification. Riboflavin may also be involved in maintaining erythrocyte integrity. This vitamin is essential for healthy skin, nails, and hair.

FDA_UNII_Code

TLM2976OFR

FULL_SYN

Riboflavin

Vitamin B2

Lactoflavin

riboflavin

6,7-Dimethyl-9-D-ribitylisoalloxazine

RIBOFLAVIN

vitamin B2

Riboflavine

INFOODS

RIBF

label

Riboflavin

Legacy_Concept_Name

Riboflavin

Micronutrient

Y

NSC_Code

33298

Nutrient

Y

PDQ_Closed_Trial_Search_ID

38330

PDQ_Open_Trial_Search_ID

38330

Preferred_Name

Riboflavin

prefixIRI

ncit:C808

Semantic_Type

Organic Chemical

Vitamin

UMLS_CUI

C0035527

Unit

mg

US_Recommended_Intake

Y

USDA_ID

405

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45812

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http://purl.bioontology.org/ontology/MEDLINEPLUS/C0035527 MedlinePlus Health Topics LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.767.405.650 Robert Hoehndorf Version of MeSH LOOM
http://purl.bioontology.org/ontology/SNMI/F-BB320 Systematized Nomenclature of Medicine, International Version LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.494.507.650 Robert Hoehndorf Version of MeSH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU007595 Logical Observation Identifier Names and Codes LOOM
http://purl.bioontology.org/ontology/RXNORM/9346 RxNORM LOOM
http://www.semanticweb.org/tome/ontologies/2015/7/Richfields#riboflavin A formal representation of the knowledge within the domain of Isotopes for Food Science LOOM
http://purl.bioontology.org/ontology/MEDDRA/10058790 Medical Dictionary for Regulatory Activities LOOM
http://purl.bioontology.org/ontology/LNC/LP15853-2 Logical Observation Identifier Names and Codes LOOM
http://www.drugbank.ca/drugs/DB00140 Functional Therapeutic Chemical Classification System LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146013 National Drug File - Reference Terminology LOOM
http://purl.jp/bio/4/id/200906001217217272 Interlinking Ontology for Biological Concepts LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D012256 Robert Hoehndorf Version of MeSH LOOM
http://purl.bioontology.org/ontology/CSP/3147-2745 Computer Retrieval of Information on Scientific Projects Thesaurus LOOM
http://purl.bioontology.org/ontology/MESH/D012256 Medical Subject Headings LOOM
http://localhost/plosthes.2017-1#4090 PLOS Thesaurus LOOM
http://purl.jp/bio/10/gmo/GMO_001037 Growth Medium Onotology LOOM
http://purl.bioontology.org/ontology/UATC/A11HA04 Anatomical Therapeutic Chemical Classification LOOM
http://www.semanticweb.org/tome/ontologies/2015/7/Richfields#Riboflavin A formal representation of the knowledge within the domain of Isotopes for Food Science LOOM
http://www.co-ode.org/ontologies/galen#Riboflavin Galen Ontology LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D08.211.474.650 Robert Hoehndorf Version of MeSH LOOM
http://purl.bioontology.org/ontology/VANDF/4017633 Veterans Health Administration National Drug File LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/13235001 SNOMED CT LOOM
http://doe-generated-ontology.com/OntoAD#C0035527 Bilingual Ontology of Alzheimer's Disease and Related Diseases LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.733.315.650 Robert Hoehndorf Version of MeSH LOOM
http://purl.bioontology.org/ontology/VANDF/4021901 Veterans Health Administration National Drug File LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000038330 Physician Data Query LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 go-plus LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 go-plus LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 BioModels Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 Neuro Behavior Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 The Drug-Drug Interactions Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 The Drug Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 go-plus LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 Human Interaction Network Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 go-plus LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 go-plus LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 Neuroscience Information Framework (NIF) Standard Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 Monarch Disease Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 FoodOn LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 Chemical Entities of Biological Interest Ontology LOOM
http://purl.obolibrary.org/obo/CHEBI_17015 Ontology for Newborn Screening Follow-up and Translational Research LOOM