loading...| Preferred Name |
Colistimethate |
|
| Synonyms |
COLISTIMETHATE Colistimethate |
|
| Definitions |
A broad-spectrum polymyxin antibiotic against most aerobic Gram-negative bacteria except Proteus bacteria. Colistimethate is a mixture of methanesulfonate derivatives of cyclic polypeptides colistin A and B from Bacillus colistinus or B. polymyxa. Colistin functions as a surfactant which penetrates into and disrupts the bacterial cell membrane, thereby resulting in bactericidal effect. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C72729 |
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| CAS_Registry |
12705-41-8 |
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| CHEBI_ID |
CHEBI:59662 |
|
| code |
C72729 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A broad-spectrum polymyxin antibiotic against most aerobic Gram-negative bacteria except Proteus bacteria. Colistimethate is a mixture of methanesulfonate derivatives of cyclic polypeptides colistin A and B from Bacillus colistinus or B. polymyxa. Colistin functions as a surfactant which penetrates into and disrupts the bacterial cell membrane, thereby resulting in bactericidal effect. |
|
| FDA_UNII_Code |
DL2R53P963 |
|
| FULL_SYN |
COLISTIMETHATE Colistimethate |
|
| Has_Salt_Form | ||
| label |
Colistimethate |
|
| Legacy Concept Name |
Colistimethate |
|
| Preferred_Name |
Colistimethate |
|
| prefixIRI |
Thesaurus:C72729 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0009315 |
|
| subClassOf |