National Cancer Institute Thesaurus

Last uploaded: February 4, 2019
Preferred Name

Cefmetazole

Synonyms

Cefmetazole

CEFMETAZOLE

Definitions

A second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefmetazole binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65297

CAS_Registry

56796-20-4

CHEBI_ID

CHEBI:3489

Chemical_Formula

C15H17N7O5S3

code

C65297

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefmetazole binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.

FDA_UNII_Code

3J962UJT8H

FULL_SYN

Cefmetazole

CEFMETAZOLE

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65298

label

Cefmetazole

Legacy_Concept_Name

Cefmetazole

Preferred_Name

Cefmetazole

prefixIRI

ncit:C65297

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0007550

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C357

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http://purl.bioontology.org/ontology/LNC/LP17800-1 LOINC LOOM
http://purl.bioontology.org/ontology/VANDF/4019660 VANDF LOOM
http://purl.bioontology.org/ontology/SNMI/C-53780 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D015311 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147752 NDFRT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/397422004 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.665.074.250.177 RH-MESH LOOM
http://purl.obolibrary.org/obo/DRON_00012888 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00012888 DRON LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/96059002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MESH/D015311 MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_3489 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3489 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3489 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_3489 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_3489 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3489 NIFSTD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.249.250.177 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/J01DC09 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.249.250.177 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001884 LOINC LOOM
http://purl.jp/bio/4/id/200906077484565049 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/004851 NDDF LOOM
http://purl.bioontology.org/ontology/RXNORM/2182 RXNORM LOOM