loading...| Preferred Name |
Cyanocobalamin |
|
| Synonyms |
Cyanocobalamin Vitamin B12 CYANOCOBALAMIN cyanocobalamin Berubigen Betalin 12 Calomist Cobavite Nascobal |
|
| Definitions |
A cobalt-containing coordination compound generated by intestinal microbes, and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C64333 |
|
| ALT_DEFINITION |
A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Cyanocobalamin helps make red blood cells, DNA, RNA, energy, and tissues, and keeps nerve cells healthy. It is found in liver, meat, eggs, poultry, shellfish, milk, and milk products. Cyanocobalamin is water-soluble (can dissolve in water) and must be taken in every day. Not enough cyanocobalamin can cause certain types of anemia (a condition in which the number of red blood cells is below normal) and neurologic disorders. It is being studied with folate in the prevention and treatment of some types of cancer. |
|
| CAS_Registry |
68-19-9 |
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| CHEBI_ID |
CHEBI:17439 |
|
| Chemical_Formula |
C63H89CoN14O14P |
|
| code |
C64333 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 |
|
| Contributing_Source |
FDA HemOnc |
|
| DEFINITION |
A cobalt-containing coordination compound generated by intestinal microbes, and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions. |
|
| FDA_UNII_Code |
P6YC3EG204 |
|
| FULL_SYN |
Cyanocobalamin Vitamin B12 CYANOCOBALAMIN cyanocobalamin Berubigen Betalin 12 Calomist Cobavite Nascobal |
|
| label |
Cyanocobalamin |
|
| Legacy Concept Name |
Cyanocobalamin |
|
| NCI_Drug_Dictionary_ID |
40295 |
|
| NSC Number |
80365 |
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| PDQ_Closed_Trial_Search_ID |
40295 |
|
| PDQ_Open_Trial_Search_ID |
40295 |
|
| Preferred_Name |
Cyanocobalamin |
|
| prefixIRI |
Thesaurus:C64333 |
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| Semantic_Type |
Pharmacologic Substance Vitamin |
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| UMLS_CUI |
C0042845 |
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| subClassOf |