loading...| Preferred Name |
Granisetron |
|
| Synonyms |
GRANISETRON granisetron 1-Methyl-N-(9-methyl-endo-9-azabicyclo(3.3.1)non-3-yl)-1H-indazole-3-carboxamide Granisetron |
|
| Definitions |
An indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62031 |
|
| Accepted_Therapeutic_Use_For |
Chemotherapy induced nausea or vomiting |
|
| ALT_DEFINITION |
The active ingredient in a drug used to treat nausea and vomiting caused by cancer treatment. Granisetron is a type of serotonin receptor antagonist and a type of antiemetic. |
|
| CAS_Registry |
109889-09-0 |
|
| Chemical_Formula |
C18H24N4O |
|
| code |
C62031 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 |
|
| Contributing_Source |
FDA HemOnc |
|
| DEFINITION |
An indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. |
|
| FDA_UNII_Code |
WZG3J2MCOL |
|
| FULL_SYN |
GRANISETRON granisetron 1-Methyl-N-(9-methyl-endo-9-azabicyclo(3.3.1)non-3-yl)-1H-indazole-3-carboxamide Granisetron |
|
| Has_Salt_Form | ||
| label |
Granisetron |
|
| Legacy Concept Name |
Granisetron_Base |
|
| NCI_Drug_Dictionary_ID |
794007 |
|
| PDQ_Closed_Trial_Search_ID |
794007 |
|
| PDQ_Open_Trial_Search_ID |
794007 |
|
| Preferred_Name |
Granisetron |
|
| prefixIRI |
Thesaurus:C62031 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0061863 |
|
| subClassOf |