National Cancer Institute Thesaurus

Last uploaded: August 27, 2019
Preferred Name

Spectinomycin

Synonyms

SPECTINOMYCIN

Spectinomycin

Definitions

An aminocyclitol aminoglycoside antibiotic derived from Streptomyces spectabilis with bacteriostatic activity. Spectinomycin binds to the bacterial 30S ribosomal subunit. As a result, this agent interferes with the initiation of protein synthesis and with proper protein elongation. This eventually leads to bacterial cell death.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61951

CAS_Registry

1695-77-8

Chemical_Formula

C14H24N2O7

code

C61951

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An aminocyclitol aminoglycoside antibiotic derived from Streptomyces spectabilis with bacteriostatic activity. Spectinomycin binds to the bacterial 30S ribosomal subunit. As a result, this agent interferes with the initiation of protein synthesis and with proper protein elongation. This eventually leads to bacterial cell death.

FDA_UNII_Code

93AKI1U6QF

FULL_SYN

SPECTINOMYCIN

Spectinomycin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90691

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47728

label

Spectinomycin

Legacy_Concept_Name

Spectinomycin

Preferred_Name

Spectinomycin

prefixIRI

ncit:C61951

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0001268

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2363

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http://purl.jp/bio/4/id/200906018945375453 IOBC LOOM
http://purl.jp/bio/4/id/200906018945375453 IOBC LOOM
http://purl.jp/bio/4/id/200906018945375453 IOBC LOOM
http://purl.jp/bio/4/id/200906018945375453 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/270 RXNORM LOOM
http://purl.obolibrary.org/obo/dinto_DB00919 DINTO LOOM
http://purl.bioontology.org/ontology/RCD/eb6.. RCD LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148017 NDFRT LOOM
http://purl.obolibrary.org/obo/ARO_0000039 ARO LOOM
http://purl.obolibrary.org/obo/ARO_0000039 ARO LOOM
http://purl.bioontology.org/ontology/VANDF/4019932 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000198 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D000198 MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008480 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372882007 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_9215 CHEBI LOOM
http://www.co-ode.org/ontologies/galen#Spectinomycin GALEN LOOM
http://purl.obolibrary.org/obo/DRON_00017899 DRON LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.494.835 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D09.408.051.836 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP16381-3 LOINC LOOM
http://purl.bioontology.org/ontology/UATC/J01XX04 ATC LOOM
http://stirdf.jst.go.jp/id/200907047275488077 IOBC LOOM
http://stirdf.jst.go.jp/id/200907047275488077 IOBC LOOM
http://stirdf.jst.go.jp/id/200907047275488077 IOBC LOOM
http://stirdf.jst.go.jp/id/200907047275488077 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.231.388.712 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-52280 SNMI LOOM