National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Naphazoline

Synonyms

Ciba 2020/R

Naphazoline

Alpha-Naphthylmethyl Imidazoline

NAPHAZOLINE

Clearine

Definitions

An imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive activity. Upon ocular administration, naphazoline exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61856

CAS_Registry

835-31-4

Chemical_Formula

C14H14N2

code

C61856

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive activity. Upon ocular administration, naphazoline exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness.

FDA_UNII_Code

H231GF11BV

FULL_SYN

Ciba 2020/R

Naphazoline

Alpha-Naphthylmethyl Imidazoline

NAPHAZOLINE

Clearine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47632

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C98243

label

Naphazoline

Legacy Concept Name

Naphazoline

Preferred_Name

Naphazoline

prefixIRI

Thesaurus:C61856

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0027373

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29709

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http://purl.obolibrary.org/obo/CHEBI_7470 CHEBI LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372803000 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/ATC/S01GA01 ATC LOOM
http://purl.bioontology.org/ontology/SNMI/C-97320 SNMI LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018175 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.129.308.585 RH-MESH LOOM
http://purl.obolibrary.org/obo/dinto_DB06711 DINTO LOOM
http://purl.bioontology.org/ontology/VANDF/4019855 VANDF LOOM
http://purl.obolibrary.org/obo/CHEBI_7470 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_7470 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_7470 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_7470 DRON LOOM
http://purl.bioontology.org/ontology/ATC/R01AB02 ATC LOOM
http://stirdf.jst.go.jp/id/200907051701636795 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0027373 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C61856 BERO LOOM
http://purl.obolibrary.org/obo/OMIT_0010312 OMIT LOOM
http://purl.obolibrary.org/obo/MESH_D009278 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009278 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/7247 RXNORM LOOM
https://go.drugbank.com/drugs/DB06711 MDM LOOM
http://www.co-ode.org/ontologies/galen#Naphazoline GALEN LOOM
http://purl.jp/bio/4/id/200906036971794306 IOBC LOOM
http://www.drugbank.ca/drugs/DB06711 FTC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147941 NDFRT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8479 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D009278 MESH LOOM
http://purl.bioontology.org/ontology/RCD/x01Cb RCD LOOM
http://purl.bioontology.org/ontology/ATC/R01AA08 ATC LOOM