National Cancer Institute Thesaurus

Last uploaded: August 27, 2019
Preferred Name

Choline

Synonyms

CHOLINE

(2-Hydroxyethyl)trimethylammonium

Choline

Vitamin J

2-hydroxyethyl-trimethyl-ammonium

choline

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61674

ALT_DEFINITION

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Choline helps cells make membranes, make a neurotransmitter (a chemical that helps nerve cells communicate with other cells), and remove fat from the liver. It is found in whole milk, beef liver, eggs, soy foods, and peanuts. Choline is water-soluble (can dissolve in water) and must be taken in every day. Not enough choline can cause diseases of the heart and blood vessels and damage to the liver. A form of choline is being studied in the treatment of some types of cancer and to reduce pain and fever. Choline is also being studied together with vitamin B12 in the prevention and treatment of cancer.

Water-soluble vitamin that is a precursor for acetylcholine, phospholipids, and the methyl donor betaine. (DRI)

CAS_Registry

62-49-7

CHEBI_ID

CHEBI:15354

Chemical_Formula

C5H14NO

code

C61674

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

Contributing_Source

CRCH

CTRP

FDA

Display_Name

Choline

FDA_UNII_Code

N91BDP6H0X

FULL_SYN

CHOLINE

(2-Hydroxyethyl)trimethylammonium

Choline

Vitamin J

2-hydroxyethyl-trimethyl-ammonium

choline

INFOODS

CHOLN

label

Choline

Legacy_Concept_Name

Choline

Micronutrient

Y

Nutrient

Y

Preferred_Name

Choline

prefixIRI

ncit:C61674

Semantic_Type

Vitamin

Tolerable_Level

Y

UMLS_CUI

C0008405

Unit

mcg

US_Recommended_Intake

Y

USDA_ID

421

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1551

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http://purl.bioontology.org/ontology/CSP/0663-0420 CRISP LOOM
http://purl.jp/bio/4/id/200906097406502953 IOBC LOOM
http://purl.jp/bio/4/id/200906097406502953 IOBC LOOM
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http://www.semanticweb.org/席婷/ontologies/2019/3/untitled-ontology-62#Choline PCALION LOOM
http://www.semanticweb.org/席婷/ontologies/2019/3/untitled-ontology-62#Choline PCALION LOOM
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