National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Tropicamide

Synonyms

Tropicamide

Benzeneacetamide, N-ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)-

N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide

TROPICAMIDE

Mydral

Mydriacyl

Opticyl

Ro 1-7683

Tropicacyl

Tropimil

l-Picamide

Definitions

A synthetic muscarinic antagonist with actions similar to atropine and with an anticholinergic property. Upon ocular administration, tropicamide binds to and blocks the muscarinic receptors in the sphincter and ciliary muscle in the eye. This inhibits the responses from cholinergic stimulation, producing dilation of the pupil and paralysis of the ciliary muscle. Tropicamide is a diagnostic agent and is used to produce short-duration mydriasis and cycloplegia.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47776

CAS_Registry

1508-75-4

Chemical_Formula

C17H20N2O2

code

C47776

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic muscarinic antagonist with actions similar to atropine and with an anticholinergic property. Upon ocular administration, tropicamide binds to and blocks the muscarinic receptors in the sphincter and ciliary muscle in the eye. This inhibits the responses from cholinergic stimulation, producing dilation of the pupil and paralysis of the ciliary muscle. Tropicamide is a diagnostic agent and is used to produce short-duration mydriasis and cycloplegia.

FDA_UNII_Code

N0A3Z5XTC6

FULL_SYN

Tropicamide

Benzeneacetamide, N-ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)-

N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide

TROPICAMIDE

Mydral

Mydriacyl

Opticyl

Ro 1-7683

Tropicacyl

Tropimil

l-Picamide

label

Tropicamide

Legacy Concept Name

Tropicamide

Preferred_Name

Tropicamide

prefixIRI

Thesaurus:C47776

Semantic_Type

Organic Chemical

Pharmacologic Substance

Indicator, Reagent, or Diagnostic Aid

UMLS_CUI

C0041190

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1937

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29704

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http://purl.bioontology.org/ontology/SNOMEDCT/387526001 SNOMEDCT LOOM
https://github.com/sap218/ocimido/blob/master/ontology/ocimido.owl#OCIMIDO_00198 OCIMIDO LOOM
http://purl.obolibrary.org/obo/MESH_D014331 BERO LOOM
http://stirdf.jst.go.jp/id/200907032835278793 IOBC LOOM
http://purl.obolibrary.org/obo/NCIT_C47776 BERO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0041190 OCHV LOOM
http://purl.obolibrary.org/obo/OMIT_0015169 OMIT LOOM
http://purl.obolibrary.org/obo/dinto_DB00809 DINTO LOOM
https://go.drugbank.com/drugs/DB00809 MDM LOOM
http://doe-generated-ontology.com/OntoAD#C0041190 ONTOAD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014331 RH-MESH LOOM
http://purl.jp/bio/4/id/200906036504589952 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12598 OCHV LOOM
http://purl.bioontology.org/ontology/ATC/S01FA06 ATC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018371 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146908 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.725.942 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Tropicamide GALEN LOOM
http://www.drugbank.ca/drugs/DB00809 FTC LOOM
http://purl.bioontology.org/ontology/VANDF/4018592 VANDF LOOM
http://purl.bioontology.org/ontology/RCD/k77.. RCD LOOM
http://purl.bioontology.org/ontology/MESH/D014331 MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-97580 SNMI LOOM
http://purl.bioontology.org/ontology/RXNORM/10869 RXNORM LOOM
http://purl.obolibrary.org/obo/CHEBI_9757 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_9757 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9757 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_9757 DRON LOOM