loading...| Preferred Name |
Anidulafungin |
|
| Synonyms |
anidulafungin ANIDULAFUNGIN Anidulafungin Eraxis LY303366 |
|
| Definitions |
A cyclic lipopeptide echinocandin derivative with antifungal activity. Anidulafungin inhibits 1,3 beta-D-glucan synthase, an enzyme involved in fungal cell wall synthesis, resulting in cell lysis and death. This agent is active against Candida species and Aspergillus. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38716 |
|
| Accepted_Therapeutic_Use_For |
Candidemia |
|
| ALT_DEFINITION |
A drug that is used to treat infections caused by fungi. It belongs to the family of drugs called antifungals. |
|
| CAS_Registry |
166663-25-8 |
|
| CHEBI_ID |
CHEBI:55346 |
|
| Chemical_Formula |
C58H73N7O17 |
|
| code |
C38716 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA |
|
| DEFINITION |
A cyclic lipopeptide echinocandin derivative with antifungal activity. Anidulafungin inhibits 1,3 beta-D-glucan synthase, an enzyme involved in fungal cell wall synthesis, resulting in cell lysis and death. This agent is active against Candida species and Aspergillus. (NCI04) |
|
| Display_Name |
Anidulafungin |
|
| FDA_UNII_Code |
9HLM53094I |
|
| FULL_SYN |
anidulafungin ANIDULAFUNGIN Anidulafungin Eraxis LY303366 |
|
| label |
Anidulafungin |
|
| Legacy Concept Name |
Anidulafungin |
|
| NCI_Drug_Dictionary_ID |
328242 |
|
| PDQ_Closed_Trial_Search_ID |
328242 |
|
| PDQ_Open_Trial_Search_ID |
328242 |
|
| Preferred_Name |
Anidulafungin |
|
| prefixIRI |
Thesaurus:C38716 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C1142738 |
|
| subClassOf |