Preferred Name |
Moxifloxacin Hydrochloride |
|
Synonyms |
Moxifloxacin Hydrochloride MOXIFLOXACIN HYDROCHLORIDE Avelox BAY 128039 Moxeza Vigamox |
|
Definitions |
The hydrochloride salt of a fluoroquinolone antibacterial antibiotic. Moxifloxacin binds to and inhibits the bacterial enzymes DNA gyrase (topoisomerase II) and topoisomerase IV, resulting in inhibition of DNA replication and repair and cell death in sensitive bacterial species. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38696 |
|
Accepted_Therapeutic_Use_For |
Various bacterial infections; Bacterial Conjunctivitis |
|
ALT_DEFINITION |
A drug used to treat bacterial infections. It is a type of fluoroquinolone. |
|
CAS_Registry |
186826-86-8 |
|
CHEBI_ID |
CHEBI:7008 |
|
Chemical_Formula |
C21H24FN3O4.HCl |
|
code |
C38696 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
Contributing_Source |
CTRP FDA |
|
DEFINITION |
The hydrochloride salt of a fluoroquinolone antibacterial antibiotic. Moxifloxacin binds to and inhibits the bacterial enzymes DNA gyrase (topoisomerase II) and topoisomerase IV, resulting in inhibition of DNA replication and repair and cell death in sensitive bacterial species. |
|
Display_Name |
Moxifloxacin Hydrochloride |
|
FDA_UNII_Code |
C53598599T |
|
FULL_SYN |
Moxifloxacin Hydrochloride MOXIFLOXACIN HYDROCHLORIDE Avelox BAY 128039 Moxeza Vigamox |
|
Has_Free_Acid_Or_Base_Form | ||
label |
Moxifloxacin Hydrochloride |
|
Legacy Concept Name |
Moxifloxacin |
|
NCI_Drug_Dictionary_ID |
306456 |
|
PDQ_Closed_Trial_Search_ID |
306456 |
|
PDQ_Open_Trial_Search_ID |
306456 |
|
Preferred_Name |
Moxifloxacin Hydrochloride |
|
prefixIRI |
Thesaurus:C38696 |
|
Semantic_Type |
Pharmacologic Substance Antibiotic |
|
UMLS_CUI |
C0754517 |
|
subClassOf |