loading...| Preferred Name |
Linezolid |
|
| Synonyms |
LINEZOLID Linezolid Zyvox |
|
| Definitions |
A synthetic oxazolidinone derivative, Linezolid selectively inhibits an early step in bacterial protein synthesis and affects blood pressure through monoamine oxidase inhibition. It is effective against Gram-positive organisms, including methicillin-resistant Staphylococcus aureus strains, coagulase-negative Staphylococci, vancomycin-resistant Enterococci, and penicillin-resistant Streptococcus pneumoniae strains. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29158 |
|
| CAS_Registry |
165800-03-3 |
|
| CHEBI_ID |
CHEBI:63607 |
|
| Chemical_Formula |
C16H20FN3O4 |
|
| code |
C29158 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA |
|
| DEFINITION |
A synthetic oxazolidinone derivative, Linezolid selectively inhibits an early step in bacterial protein synthesis and affects blood pressure through monoamine oxidase inhibition. It is effective against Gram-positive organisms, including methicillin-resistant Staphylococcus aureus strains, coagulase-negative Staphylococci, vancomycin-resistant Enterococci, and penicillin-resistant Streptococcus pneumoniae strains. (NCI04) |
|
| Display_Name |
Linezolid |
|
| FDA_UNII_Code |
ISQ9I6J12J |
|
| FULL_SYN |
LINEZOLID Linezolid Zyvox |
|
| label |
Linezolid |
|
| Legacy Concept Name |
Linezolid |
|
| NCI_Drug_Dictionary_ID |
735710 |
|
| PDQ_Closed_Trial_Search_ID |
735710 |
|
| PDQ_Open_Trial_Search_ID |
735710 |
|
| Preferred_Name |
Linezolid |
|
| prefixIRI |
Thesaurus:C29158 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
|
| UMLS_CUI |
C0663241 |
|
| subClassOf |