National Cancer Institute Thesaurus

Last uploaded: October 28, 2019
Preferred Name

Hydrazine

Synonyms

Hydrazine

HYDRAZINE

Definitions

A highly reactive base and reducing agent used in many industrial and medical applications. In biological applications, hydrazine and its derivatives exhibit antidepressant properties by inhibiting monoamine oxidase (MAO), an enzyme that catalyzes the deamination and inactivation of certain stimulatory neurotransmitters such as norepinephrine and dopamine. In psychiatry, the use of hydrazine derivatives is limited due to the emergence of the tricyclic antidepressants. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29097

CAS_Registry

302-01-2

CHEBI_ID

CHEBI:15571

Chemical_Formula

H4N2

code

C29097

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A highly reactive base and reducing agent used in many industrial and medical applications. In biological applications, hydrazine and its derivatives exhibit antidepressant properties by inhibiting monoamine oxidase (MAO), an enzyme that catalyzes the deamination and inactivation of certain stimulatory neurotransmitters such as norepinephrine and dopamine. In psychiatry, the use of hydrazine derivatives is limited due to the emergence of the tricyclic antidepressants. (NCI04)

FDA_UNII_Code

27RFH0GB4R

FULL_SYN

Hydrazine

HYDRAZINE

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1129

label

Hydrazine

Legacy_Concept_Name

Hydrazine

Preferred_Name

Hydrazine

prefixIRI

ncit:C29097

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0020231

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1935

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C667

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