National Cancer Institute Thesaurus

Last uploaded: February 25, 2019
Preferred Name

Gatifloxacin

Synonyms

Gatifloxacin

GATIFLOXACIN

Zymar

Gatiflo

AM-1155

1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid

Tequin

BMS-206584-01

Definitions

A synthetic 8-methoxyfluoroquinolone with antibacterial activity against a wide range of gram-negative and gram-positive microorganisms. Gatifloxacin exerts its effect through inhibition of DNA gyrase, an enzyme involved in DNA replication, transcription and repair, and inhibition of topoisomerase IV, an enzyme involved in partitioning of chromosomal DNA during bacterial cell division.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29070

CAS_Registry

112811-59-3

180200-66-2

CHEBI_ID

CHEBI:5280

Chemical_Formula

2C19H22FN3O4.3H2O

code

C29070

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic 8-methoxyfluoroquinolone with antibacterial activity against a wide range of gram-negative and gram-positive microorganisms. Gatifloxacin exerts its effect through inhibition of DNA gyrase, an enzyme involved in DNA replication, transcription and repair, and inhibition of topoisomerase IV, an enzyme involved in partitioning of chromosomal DNA during bacterial cell division.

FDA_UNII_Code

L4618BD7KJ

FULL_SYN

Gatifloxacin

GATIFLOXACIN

Zymar

Gatiflo

AM-1155

1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid

Tequin

BMS-206584-01

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132281

label

Gatifloxacin

Legacy_Concept_Name

Gatifloxacin

Preferred_Name

Gatifloxacin

prefixIRI

ncit:C29070

Semantic_Type

Antibiotic

UMLS_CUI

C0753645

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C795

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http://purl.obolibrary.org/obo/CHEBI_5280 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_5280 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_5280 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_5280 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_5280 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_5280 CHEBI LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/371238005 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/LP28719-0 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU014634 LOINC LOOM
http://purl.bioontology.org/ontology/NDDF/007995 NDDF LOOM
http://purl.bioontology.org/ontology/VANDF/4021187 VANDF LOOM
http://purl.bioontology.org/ontology/UATC/J01MA16 ATC LOOM
http://purl.bioontology.org/ontology/MESH/C078049 MESH LOOM
http://purl.jp/bio/4/id/200906099719099702 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C078049 RH-MESH LOOM
http://purl.bioontology.org/ontology/UATC/S01AE06 ATC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148634 NDFRT LOOM
http://purl.obolibrary.org/obo/DRON_00016731 ODNAE LOOM
http://purl.obolibrary.org/obo/DRON_00016731 DRON LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005577 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005577 DMTO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148634 ODAE LOOM
http://purl.bioontology.org/ontology/RXNORM/228476 RXNORM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/116349004 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005570 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005570 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005570 DMTO LOOM