National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Dextroamphetamine

Synonyms

DEXTROAMPHETAMINE

Dextroamphetamine

(+)-Amphetamine

Definitions

A synthetic substance related to natural sympathomimetic amines and the synthetic agent amphetamine. In the central nervous system (CNS), dextroamphetamine induces the release of dopamine within the mesocorticolimbic system, a major component of the brain reward system, resulting in measurable behavioral changes such as euphoria. As a CNS stimulant, this agent may increase blood pressure and reduce appetite. Similar to other amphetamines, dextroamphetamine has a high potential for abuse, dependence, and addiction if used in large doses over extended periods of time. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28981

CAS_Registry

51-64-9

CHEBI_ID

CHEBI:4469

Chemical_Formula

C9H13N

code

C28981

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic substance related to natural sympathomimetic amines and the synthetic agent amphetamine. In the central nervous system (CNS), dextroamphetamine induces the release of dopamine within the mesocorticolimbic system, a major component of the brain reward system, resulting in measurable behavioral changes such as euphoria. As a CNS stimulant, this agent may increase blood pressure and reduce appetite. Similar to other amphetamines, dextroamphetamine has a high potential for abuse, dependence, and addiction if used in large doses over extended periods of time. (NCI04)

FDA_UNII_Code

TZ47U051FI

FULL_SYN

DEXTROAMPHETAMINE

Dextroamphetamine

(+)-Amphetamine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47482

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76622

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61708

label

Dextroamphetamine

Legacy Concept Name

Dextroamphetamine

NSC Number

126789

73713

Preferred_Name

Dextroamphetamine

prefixIRI

Thesaurus:C28981

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0011812

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47795

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/MESH_D003913 BERO LOOM
http://purl.bioontology.org/ontology/VANDF/4019978 VANDF LOOM
http://purl.obolibrary.org/obo/CHEBI_4469 FIDEO LOOM
http://purl.obolibrary.org/obo/OMIT_0005189 OMIT LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Dextroamphetamine APAONTO LOOM
https://go.drugbank.com/drugs/DB01576 MDM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0011812 OCHV LOOM
http://purl.bioontology.org/ontology/NDDF/001793 NDDF LOOM
http://purl.bioontology.org/ontology/CSP/2268-4149 CRISP LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3828 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C28981 BERO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004761 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003913 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP18019-7 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387278002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/SNMI/C-65020 SNMI LOOM
http://www.case.edu/EpSO.owl#Dextroamphetamine MEPO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.471.683.152.110.200 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB01576 FTC LOOM
http://purl.bioontology.org/ontology/MESH/D003913 MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016153 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RXNORM/3288 RXNORM LOOM
http://www.case.edu/EpilepsyOntology.owl#Dextroamphetamine EPSO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148062 NDFRT LOOM