loading...| Preferred Name |
Vascular Endothelial Growth Factor Receptor 3 |
|
| Synonyms |
Vascular Endothelial Growth Factor Receptor 3 EC 2.7.10.1 FMS-Like Tyrosine Kinase 4 FMS-Related Tyrosine Kinase 4 Tyrosine-Protein Kinase Receptor FLT4 AV3 FLT4 VEGFR-3 VEGFR3 |
|
| Definitions |
Vascular endothelial growth factor receptor 3 (1363 aa, ~153 kDa) is encoded by the human FLT4 gene. This protein is involved in tyrosine phosphorylation, lymph vessel formation and ligand-dependent signaling. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26203 |
|
| code |
C26203 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP |
|
| DEFINITION |
Vascular endothelial growth factor receptor 3 (1363 aa, ~153 kDa) is encoded by the human FLT4 gene. This protein is involved in tyrosine phosphorylation, lymph vessel formation and ligand-dependent signaling. |
|
| DesignNote |
A type I membrane protein tyrosine kinase receptor for VEGF-C, vascular endothelial growth factor receptor 3, contains seven immunoglobulin-like C2-type domains. Vascular endothelial growth factors, working through VEGF receptor-3, promote angiogenesis and metastatic spread of cancer cells. (from Nat Med 2001. 7:151 & 186) |
|
| Display_Name |
Vascular Endothelial Growth Factor Receptor 3 |
|
| FULL_SYN |
Vascular Endothelial Growth Factor Receptor 3 EC 2.7.10.1 FMS-Like Tyrosine Kinase 4 FMS-Related Tyrosine Kinase 4 Tyrosine-Protein Kinase Receptor FLT4 AV3 FLT4 VEGFR-3 VEGFR3 |
|
| label |
Vascular Endothelial Growth Factor Receptor 3 |
|
| Legacy Concept Name |
FMS-Related_Tyrosine_Kinase-4 |
|
| OMIM_Number |
136352 |
|
| Preferred_Name |
Vascular Endothelial Growth Factor Receptor 3 |
|
| prefixIRI |
Thesaurus:C26203 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme Receptor |
|
| Swiss_Prot |
P35916 |
|
| UMLS_CUI |
C3657407 |
|
| subClassOf |