National Cancer Institute Thesaurus

Last uploaded: February 4, 2019
Preferred Name

Celecoxib

Synonyms

CELECOXIB

celecoxib

Celebrex

YM 177

SC-58635

Celecoxib

4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide

Benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-

Definitions

A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1728

Accepted_Therapeutic_Use_For

Acute pain; Familial adenomatous polyposis; Primary dysmenorrhea; Osteoarthritis; Rheumatoid arthritis

ALT_DEFINITION

A drug that reduces pain. Celecoxib belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is being studied in the prevention of cancer.

CAS_Registry

169590-42-5

CHEBI_ID

CHEBI:41423

Chemical_Formula

C17H14F3N3O2S

code

C1728

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

Contributing_Source

CTRP

FDA

DEFINITION

A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis.

Display_Name

Celecoxib

FDA_UNII_Code

JCX84Q7J1L

FULL_SYN

CELECOXIB

celecoxib

Celebrex

YM 177

SC-58635

Celecoxib

4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide

Benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-

label

Celecoxib

Legacy_Concept_Name

Celecoxib

NSC_Code

719627

PDQ_Closed_Trial_Search_ID

43023

PDQ_Open_Trial_Search_ID

43023

Preferred_Name

Celecoxib

prefixIRI

ncit:C1728

Semantic_Type

Pharmacologic Substance

Organic Chemical

UMLS_CUI

C0538927

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80509

Delete Subject Author Type Created
No notes to display
Create New Mapping

Delete Mapping To Ontology Source
http://www.drugbank.ca/drugs/DB00482 FTC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C105934 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/370187009 SNOMEDCT LOOM
http://bmi.utah.edu/ontologies/peontology/C0538927 RAO LOOM
http://purl.bioontology.org/ontology/RXNORM/140587 RXNORM LOOM
http://purl.obolibrary.org/obo/CHEBI_41423 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_41423 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_41423 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_41423 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_41423 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_41423 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_41423 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_41423 NIFSTD LOOM
http://doe-generated-ontology.com/OntoAD#C0538927 ONTOAD LOOM
http://purl.bioontology.org/ontology/VANDF/4021143 VANDF LOOM
http://purl.bioontology.org/ontology/UATC/L01XX33 ATC LOOM
http://scai.fraunhofer.de/AlzheimerOntology#celecoxib ADO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148596 NDFRT LOOM
http://purl.bioontology.org/ontology/MESH/D000068579 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/116081000 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/UATC/M01AH01 ATC LOOM
http://purl.obolibrary.org/obo/DRON_00014627 DRON LOOM
http://www.co-ode.org/ontologies/galen#Celecoxib GALEN LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000043023 PDQ LOOM
http://purl.jp/bio/4/id/200906068548516927 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LP28519-4 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU013163 LOINC LOOM