loading...| Preferred Name |
Celecoxib |
|
| Synonyms |
Benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]- 4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide CELECOXIB Celebrex Celecoxib SC-58635 YM 177 celecoxib |
|
| Definitions |
A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1728 |
|
| Accepted_Therapeutic_Use_For |
Acute pain; Familial adenomatous polyposis; Primary dysmenorrhea; Osteoarthritis; Rheumatoid arthritis |
|
| ALT_DEFINITION |
A drug that reduces pain. Celecoxib belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is being studied in the prevention of cancer. |
|
| CAS_Registry |
169590-42-5 |
|
| CHEBI_ID |
CHEBI:41423 |
|
| Chemical_Formula |
C17H14F3N3O2S |
|
| code |
C1728 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
CTRP FDA GDC |
|
| DEFINITION |
A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis. |
|
| Display_Name |
Celecoxib |
|
| FDA_UNII_Code |
JCX84Q7J1L |
|
| FULL_SYN |
Benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]- 4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide CELECOXIB Celebrex Celecoxib SC-58635 YM 177 celecoxib |
|
| Has_Target | ||
| Is_Value_For_GDC_Property | ||
| label |
Celecoxib |
|
| Legacy Concept Name |
Celecoxib |
|
| Maps_To |
Celecoxib |
|
| NCI_Drug_Dictionary_ID |
43023 |
|
| NSC Number |
719627 |
|
| PDQ_Closed_Trial_Search_ID |
43023 |
|
| PDQ_Open_Trial_Search_ID |
43023 |
|
| Preferred_Name |
Celecoxib |
|
| prefixIRI |
Thesaurus:C1728 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0538927 |
|
| subClassOf |