loading...| Preferred Name |
Vilanterol |
|
| Synonyms |
GW 642444 GW-642444 GW642444 VILANTEROL Vilanterol |
|
| Definitions |
A long-acting beta-2 adrenergic agonist, with bronchodilator activity. Upon administration, vilanterol stimulates beta-2 adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C152875 |
|
| CAS_Registry |
503068-34-6 |
|
| code |
C152875 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A long-acting beta-2 adrenergic agonist, with bronchodilator activity. Upon administration, vilanterol stimulates beta-2 adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. |
|
| FDA_UNII_Code |
028LZY775B |
|
| FULL_SYN |
GW 642444 GW-642444 GW642444 VILANTEROL Vilanterol |
|
| label |
Vilanterol |
|
| NCI_Drug_Dictionary_ID |
804498 |
|
| PDQ_Closed_Trial_Search_ID |
804498 |
|
| PDQ_Open_Trial_Search_ID |
804498 |
|
| Preferred_Name |
Vilanterol |
|
| prefixIRI |
Thesaurus:C152875 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C2935023 |
|
| subClassOf |