National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Protein Kinase C Delta Type

Synonyms

EC 2.7.11.13

Tyrosine-Protein Kinase PRKCD

Protein Kinase C Delta Type

EC 2.7.10.2

PRKCD

nPKC-Delta

Definitions

Protein kinase C delta type (676 aa, ~78 kDa) is encoded by the human PRKCD gene. This protein plays a role in the regulation of apoptosis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150120

code

C150120

DEFINITION

Protein kinase C delta type (676 aa, ~78 kDa) is encoded by the human PRKCD gene. This protein plays a role in the regulation of apoptosis.

DesignNote

Protein kinase C delta type is cleaved by caspase-3 to yield a regulatory subunit and a catalytic subunit and results in activation of kinase activity. The catalytic subunit is also known as sphingosine-dependent protein kinase-1 (SDK1). (UniProt)

Protein kinase C delta type may possess tyrosine-protein kinase activity. (UniProt)

FULL_SYN

EC 2.7.11.13

Tyrosine-Protein Kinase PRKCD

Protein Kinase C Delta Type

EC 2.7.10.2

PRKCD

nPKC-Delta

label

Protein Kinase C Delta Type

OMIM_Number

176977

Preferred_Name

Protein Kinase C Delta Type

prefixIRI

Thesaurus:C150120

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Swiss_Prot

Q05655

UMLS_CUI

C1566443

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17325

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