loading...| Preferred Name |
Penicillin Antibiotic |
|
| Synonyms |
Penicillin Antibiotic penicillin |
|
| Definitions |
Any beta-lactam antibiotic derived from Penicillium fungi with bactericidal activity. Penicillin antibiotics bind to and inactivate penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1500 |
|
| ALT_DEFINITION |
A drug that is used to treat infection. It belongs to the family of drugs called antibiotics. |
|
| CHEBI_ID |
CHEBI:17334 |
|
| code |
C1500 |
|
| DEFINITION |
Any beta-lactam antibiotic derived from Penicillium fungi with bactericidal activity. Penicillin antibiotics bind to and inactivate penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis. |
|
| FULL_SYN |
Penicillin Antibiotic penicillin |
|
| label |
Penicillin Antibiotic |
|
| Legacy Concept Name |
Penicillin_Antibiotic |
|
| Preferred_Name |
Penicillin Antibiotic |
|
| prefixIRI |
Thesaurus:C1500 |
|
| Semantic_Type |
Organic Chemical Antibiotic |
|
| UMLS_CUI |
C0030842 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/NCIT_C1500 | BERO | LOOM |