National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Pyruvate

Synonyms

Propanoic Acid, 2-Oxo-, Ion(1-)

2-Oxopropanoate

Pyruvate

Definitions

A 2-oxo monocarboxylic acid anion that is the conjugate base of pyruvic acid, which is an important metabolic product for energy-producing biochemical pathways. Pyruvate is the final product of glycolysis and, when hypoxic conditions arise, can be metabolized anaerobically to form lactate. This chemical is a precursor of both acetyl-coenzyme A and oxaloacetate, which are involved in the citric acid cycle. Additionally, oxaloacetate is a substrate in the gluconeogenesis pathway.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116012

CAS_Registry

57-60-3

CHEBI_ID

CHEBI:15361

code

C116012

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

A 2-oxo monocarboxylic acid anion that is the conjugate base of pyruvic acid, which is an important metabolic product for energy-producing biochemical pathways. Pyruvate is the final product of glycolysis and, when hypoxic conditions arise, can be metabolized anaerobically to form lactate. This chemical is a precursor of both acetyl-coenzyme A and oxaloacetate, which are involved in the citric acid cycle. Additionally, oxaloacetate is a substrate in the gluconeogenesis pathway.

Display_Name

Pyruvate

FULL_SYN

Propanoic Acid, 2-Oxo-, Ion(1-)

2-Oxopropanoate

Pyruvate

label

Pyruvate

Preferred_Name

Pyruvate

prefixIRI

Thesaurus:C116012

Semantic_Type

Organic Chemical

UMLS_CUI

C0244104

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C345

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_15361 MAXO LOOM
http://purl.bioontology.org/ontology/CSP/1129-3692 CRISP LOOM
http://localhost/plosthes.2017-1#6438 PLOSTHES LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 OBA LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 MAXO LOOM
http://purl.obolibrary.org/obo/CHEBI_15361 ZP LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003184 LOINC LOOM
http://purl.bioontology.org/ontology/CPT/84210 CPT LOOM
http://purl.bioontology.org/ontology/LNC/LP15693-2 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LP32146-0 LOINC LOOM
http://www.projecthalo.com/aura#Pyruvate AURA LOOM
http://www.semanticweb.org/ADMO#pyruvate ADMO LOOM
http://purl.bioontology.org/ontology/RXNORM/72031 RXNORM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/430640006 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#25111 OCHV LOOM
http://purl.bioontology.org/ontology/SNMI/F-61040 SNMI LOOM
http://purl.bioontology.org/ontology/RCD/X80Ij RCD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0034354 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C116012 BERO LOOM
http://purl.obolibrary.org/obo/NCIT_C116012 ONS LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0244104 OCHV LOOM
http://purl.obolibrary.org/obo/UPa_UPC00022 UPA LOOM
http://purl.bioontology.org/ontology/MEDDRA/10037677 MEDDRA LOOM
http://id.nlm.nih.gov/mesh/D019289 MDM LOOM