National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

Ibutamoren
Synonyms

2-amino-n-((r)-2-(benzyloxy)-1-((1-(methylsulfonyl)spiro(indoline-3,4'-piperidin)-1'-yl)carbonyl)ethyl)-2-methylpropionamide

IBUTAMOREN

Ibutamoren

L 163191
Definitions

An orally bioavailable, small molecule, non-peptide growth hormone secretagogue (GHS). Upon administration, ibutamoren promotes the release of growth hormone (GH) from the pituitary gland, thereby increasing plasma GH levels. This may counteract GH deficiency. GH plays an important role in many biological processes.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97488
CAS_Registry

159634-47-6
Chemical_Formula

C27H36N4O5S
code

C97488
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923
Contributing_Source

FDA
DEFINITION

An orally bioavailable, small molecule, non-peptide growth hormone secretagogue (GHS). Upon administration, ibutamoren promotes the release of growth hormone (GH) from the pituitary gland, thereby increasing plasma GH levels. This may counteract GH deficiency. GH plays an important role in many biological processes.
FDA_UNII_Code

GJ0EGN38UL
FULL_SYN

2-amino-n-((r)-2-(benzyloxy)-1-((1-(methylsulfonyl)spiro(indoline-3,4'-piperidin)-1'-yl)carbonyl)ethyl)-2-methylpropionamide

IBUTAMOREN

Ibutamoren

L 163191
Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C97489
label

Ibutamoren
Preferred_Name

Ibutamoren
prefixIRI

Thesaurus:C97488
Semantic_Type

Pharmacologic Substance
UMLS_CUI

C0300147
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1910
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