loading...| Preferred Name |
Vindesine Sulfate |
|
| Synonyms |
VINDESINE SULFATE Vindesine Sulphate Vindesini Sulfas Desacetyl Vinblastine Amide Sulfate Vindesine sulfate Vindesine Sulfate Eldesine Eldisin Eldisine Enison Fildesin Gesidine LY-099094 |
|
| Definitions |
The sulfate salt form of Vindesine. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C935 |
|
| CAS_Registry |
59917-39-4 |
|
| CHEBI_ID |
CHEBI:32295 |
|
| Chemical_Formula |
C43H55N5O7.H2O4S |
|
| code |
C935 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The sulfate salt form of Vindesine. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI) |
|
| FDA_UNII_Code |
CPH2U7DNDY |
|
| FULL_SYN |
VINDESINE SULFATE Vindesine Sulphate Vindesini Sulfas Desacetyl Vinblastine Amide Sulfate Vindesine sulfate Vindesine Sulfate Eldesine Eldisin Eldisine Enison Fildesin Gesidine LY-099094 |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Vindesine Sulfate |
|
| Legacy Concept Name |
Vindesine_Sulfate |
|
| NCI_Drug_Dictionary_ID |
39732 |
|
| NSC Number |
245467 |
|
| PDQ_Closed_Trial_Search_ID |
39732 |
|
| PDQ_Open_Trial_Search_ID |
39732 |
|
| Preferred_Name |
Vindesine Sulfate |
|
| prefixIRI |
Thesaurus:C935 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0042683 |
|
| subClassOf |