National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Paraben

Synonyms

Paraben Derivatives

para-Hydroxybenzoic Acid Ester

Paraben

Parabens

Definitions

An alkyl ester of p-hydroxybenzoic acid (PHBA) that is used most often as a preservative in various personal care products. Parabens are active against a broad spectrum of microorganisms and exert their activity by disrupting the integrity of the cell membrane, causing leakage of intracellular proteins and interference with membrane transport processes, by inhibiting synthesis of DNA and RNA or by inhibiting the activity of certain enzymes, such as ATPases and phosphotransferases.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C92608

code

C92608

DEFINITION

An alkyl ester of p-hydroxybenzoic acid (PHBA) that is used most often as a preservative in various personal care products. Parabens are active against a broad spectrum of microorganisms and exert their activity by disrupting the integrity of the cell membrane, causing leakage of intracellular proteins and interference with membrane transport processes, by inhibiting synthesis of DNA and RNA or by inhibiting the activity of certain enzymes, such as ATPases and phosphotransferases.

FULL_SYN

Paraben Derivatives

para-Hydroxybenzoic Acid Ester

Paraben

Parabens

label

Paraben

Preferred_Name

Paraben

prefixIRI

Thesaurus:C92608

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0030398

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45678

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