National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Vecuronium

Synonyms

Vercuronium

Piperidinium, 1-((2Beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl)-1-methyl-

VECURONIUM

Vecuronium

Definitions

A synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity. Vecuronium competitively binds to and blocks the nicotinic acetylcholine receptor at the neuromuscular junction, thereby preventing acetylcholine (ACh) binding and resulting in skeletal muscle relaxation and paralysis. Vecuronium has a shorter duration of action than pancuronium.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C87317

CAS_Registry

86029-43-8

CHEBI_ID

CHEBI:9939

Chemical_Formula

C34H57N2O4

code

C87317

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

A synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity. Vecuronium competitively binds to and blocks the nicotinic acetylcholine receptor at the neuromuscular junction, thereby preventing acetylcholine (ACh) binding and resulting in skeletal muscle relaxation and paralysis. Vecuronium has a shorter duration of action than pancuronium.

Display_Name

Vecuronium

FDA_UNII_Code

5438723848

FULL_SYN

Vercuronium

Piperidinium, 1-((2Beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl)-1-methyl-

VECURONIUM

Vecuronium

label

Vecuronium

Preferred_Name

Vecuronium

prefixIRI

Thesaurus:C87317

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0242531

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66886

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