National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Tedizolid

Synonyms

2-Oxazolidinone, 3-(3-Fluoro-4-(6-(2-Methyl-2H-Tetrazol-5-yl)-3-Pyridinyl)Phenyl)-5-(Hydroxymethyl)-, (5R)-

(5R)-3-(3-Fluoro-4-(6-(2-Methyl-2H-Tetrazol-5-yl)Pyridin-3-yl)Phenyl)-5-(Hydroxymethyl)Oxazolidin-2-One

TEDIZOLID

TR-700

Tedizolid

Torezolid

Definitions

An antibacterial agent of the oxazolidinone class, that is used for the treatment of acute bacterial skin and skin structure infections caused by certain Gram-positive microorganisms. Upon intravenous administration, tedizolid targets and binds to the 50S subunit of the bacterial ribosome. This inhibits bacterial protein synthesis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C84222

CAS_Registry

856866-72-3

Chemical_Formula

C17H15FN6O3

code

C84222

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An antibacterial agent of the oxazolidinone class, that is used for the treatment of acute bacterial skin and skin structure infections caused by certain Gram-positive microorganisms. Upon intravenous administration, tedizolid targets and binds to the 50S subunit of the bacterial ribosome. This inhibits bacterial protein synthesis.

FDA_UNII_Code

97HLQ82NGL

FULL_SYN

2-Oxazolidinone, 3-(3-Fluoro-4-(6-(2-Methyl-2H-Tetrazol-5-yl)-3-Pyridinyl)Phenyl)-5-(Hydroxymethyl)-, (5R)-

(5R)-3-(3-Fluoro-4-(6-(2-Methyl-2H-Tetrazol-5-yl)Pyridin-3-yl)Phenyl)-5-(Hydroxymethyl)Oxazolidin-2-One

TEDIZOLID

TR-700

Tedizolid

Torezolid

label

Tedizolid

Preferred_Name

Tedizolid

prefixIRI

Thesaurus:C84222

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C2744850

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C258

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