loading...| Preferred Name |
Pyridoxal Phosphate |
|
| Synonyms |
Pyridoxal Phosphate PYRIDOXAL PHOSPHATE |
|
| Definitions |
The active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81627 |
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| CAS_Registry |
41468-25-1 |
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| Chemical_Formula |
C8H10NO6P.H2O |
|
| code |
C81627 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction. |
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| FDA_UNII_Code |
5V5IOJ8338 |
|
| FULL_SYN |
Pyridoxal Phosphate PYRIDOXAL PHOSPHATE |
|
| label |
Pyridoxal Phosphate |
|
| Legacy Concept Name |
Pyridoxal_Phosphate |
|
| NCI_Drug_Dictionary_ID |
804854 |
|
| Preferred_Name |
Pyridoxal Phosphate |
|
| prefixIRI |
Thesaurus:C81627 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0034266 |
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| subClassOf |