loading...| Preferred Name |
Povidone-Iodine |
|
| Synonyms |
Povidone-Iodine Solution Iodopovidone Povidone iodine Iodine Povidone Topical POVIDONE-IODINE Povidone-Iodine Povidone-iodine Betadine E-Z Prep E-Z Scrub PVP iodine PVP-I PVP-Iodine Traumasept Ultradine Videne |
|
| Definitions |
An iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the polyvinylpyrrolidone iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds. This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses. Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C766 |
|
| CAS_Registry |
25655-41-8 |
|
| code |
C766 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA |
|
| DEFINITION |
An iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the polyvinylpyrrolidone iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds. This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses. Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells. |
|
| Display_Name |
Povidone-Iodine |
|
| FDA_UNII_Code |
85H0HZU99M |
|
| FULL_SYN |
Povidone-Iodine Solution Iodopovidone Povidone iodine Iodine Povidone Topical POVIDONE-IODINE Povidone-Iodine Povidone-iodine Betadine E-Z Prep E-Z Scrub PVP iodine PVP-I PVP-Iodine Traumasept Ultradine Videne |
|
| label |
Povidone-Iodine |
|
| Legacy Concept Name |
Povidone-Iodine |
|
| NCI_Drug_Dictionary_ID |
539730 |
|
| NSC Number |
26245 |
|
| PDQ_Closed_Trial_Search_ID |
539730 |
|
| PDQ_Open_Trial_Search_ID |
539730 |
|
| Preferred_Name |
Povidone-Iodine |
|
| prefixIRI |
Thesaurus:C766 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
|
| UMLS_CUI |
C3249825 |
|
| subClassOf |