National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Betrixaban

Synonyms

Benzamide, N-(5-chloro-2-pyridinyl)-2-((4-((dimethylamino)iminomethyl)benzoyl)amino)-5-methoxy-

N-(5-Chloropyridin-2-yl)-2-((4-(N,N-dimethylcarbamimidoyl)benzoyl)amino)-5- Methoxybenzamide

BETRIXABAN

Betrixaban

Bevyxxa

PRT-054021

Definitions

An orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Betrixaban is primarily excreted unchanged in the bile and has a half life of about 19 hours.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C75154

Accepted_Therapeutic_Use_For

prophylaxis of venous thromboembolism (VTE)

CAS_Registry

330942-05-7

Chemical_Formula

C23H22ClN5O3

code

C75154

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

HemOnc

DEFINITION

An orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Betrixaban is primarily excreted unchanged in the bile and has a half life of about 19 hours.

Display_Name

Betrixaban

FDA_UNII_Code

74RWP7W0J9

FULL_SYN

Benzamide, N-(5-chloro-2-pyridinyl)-2-((4-((dimethylamino)iminomethyl)benzoyl)amino)-5-methoxy-

N-(5-Chloropyridin-2-yl)-2-((4-(N,N-dimethylcarbamimidoyl)benzoyl)amino)-5- Methoxybenzamide

BETRIXABAN

Betrixaban

Bevyxxa

PRT-054021

label

Betrixaban

Legacy Concept Name

Betrixaban

Preferred_Name

Betrixaban

prefixIRI

Thesaurus:C75154

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C2698385

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173067

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C180619

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