National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Phosphodiesterase Inhibitor

Synonyms

Phosphodiesterase Inhibitor

PDE Inhibitor

Definitions

Any substance that inhibits phosphodiesterase, an enzyme that catalyzes the breaking of a phosphodiester bond. Usually, this refers to cyclic nucleotide phosphodiesterase, an enzyme that breaks the phosphodiester bond in the second messenger molecules cAMP and cGMP. Inhibition of cyclic nucleotide phosphodiesterase can be used to affect vasodilation.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C744

CHEBI_ID

CHEBI:50218

code

C744

DEFINITION

Any substance that inhibits phosphodiesterase, an enzyme that catalyzes the breaking of a phosphodiester bond. Usually, this refers to cyclic nucleotide phosphodiesterase, an enzyme that breaks the phosphodiester bond in the second messenger molecules cAMP and cGMP. Inhibition of cyclic nucleotide phosphodiesterase can be used to affect vasodilation.

FULL_SYN

Phosphodiesterase Inhibitor

PDE Inhibitor

label

Phosphodiesterase Inhibitor

Legacy Concept Name

Phosphodiesterase_Inhibitor

Preferred_Name

Phosphodiesterase Inhibitor

prefixIRI

Thesaurus:C744

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0031638

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C471

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