National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Raltegravir

Synonyms

Raltegravir

RALTEGRAVIR

N-(2-(4-(4-Fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide

MK-0518

Definitions

A small molecule with activity against human immunodeficiency virus (HIV). Raltegravir is an integrase inhibitor that blocks the integration of the viral genome into the host DNA, a critical step in the pathogenesis of HIV.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C72837

CAS_Registry

518048-05-0

Chemical_Formula

C20H21FN6O5

code

C72837

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A small molecule with activity against human immunodeficiency virus (HIV). Raltegravir is an integrase inhibitor that blocks the integration of the viral genome into the host DNA, a critical step in the pathogenesis of HIV.

FDA_UNII_Code

22VKV8053U

FULL_SYN

Raltegravir

RALTEGRAVIR

N-(2-(4-(4-Fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide

MK-0518

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73823

label

Raltegravir

Legacy Concept Name

Raltegravir

Preferred_Name

Raltegravir

prefixIRI

Thesaurus:C72837

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C1871526

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157401

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