National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Cotinine

Synonyms

S-(-)-Cotinine

1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone

(S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone

COTININE

Cotinine

Definitions

The major metabolite of nicotine.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C70941

CAS_Registry

486-56-6

Chemical_Formula

C10H12N2O

code

C70941

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

The major metabolite of nicotine.

DesignNote

Exposure to nicotine can be measured by analyzing the cotinine level in the blood, saliva, or urine. Cotinine assays provide an objective quantitative measure that is more reliable than smoking histories or counting the number of cigarettes smoked per day. Cotinine also permits the measurement of exposure to second-hand smoke (passive smoking).

Display_Name

Cotinine

FDA_UNII_Code

K5161X06LL

FULL_SYN

S-(-)-Cotinine

1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone

(S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone

COTININE

Cotinine

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C80524

label

Cotinine

Legacy Concept Name

Cotinine

Preferred_Name

Cotinine

prefixIRI

Thesaurus:C70941

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0010194

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C73579

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