National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Sodium Phenylacetate

Synonyms

SODIUM PHENYLACETATE

Sodium Phenylacetate

Sodium phenylacetate

Definitions

The sodium salt form of phenylacetate with ammonia detoxifying activity. Upon administration, sodium phenylacetate binds to glutamine thereby forming phenylacetylglutamine and is thus excreted by the kidneys. By serving as an alternative to urea for the excretion of waste nitrogen, sodium phenylacetate is able to lower ammonia levels in the blood and prevent hyperammonemia.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66723

CAS_Registry

114-70-5

Chemical_Formula

C8H7O2.Na

code

C66723

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The sodium salt form of phenylacetate with ammonia detoxifying activity. Upon administration, sodium phenylacetate binds to glutamine thereby forming phenylacetylglutamine and is thus excreted by the kidneys. By serving as an alternative to urea for the excretion of waste nitrogen, sodium phenylacetate is able to lower ammonia levels in the blood and prevent hyperammonemia.

FDA_UNII_Code

48N6U1781G

FULL_SYN

SODIUM PHENYLACETATE

Sodium Phenylacetate

Sodium phenylacetate

label

Sodium Phenylacetate

Legacy Concept Name

Sodium_Phenylacetate

NSC Number

3039

Preferred_Name

Sodium Phenylacetate

prefixIRI

Thesaurus:C66723

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0142910

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78275

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