loading...| Preferred Name |
Cefpodoxime |
|
| Synonyms |
Cefpodoxime CEFPODOXIME |
|
| Definitions |
A third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefpodoxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefpodoxime inhibits bacterial septum and cell wall synthesis formation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65305 |
|
| CAS_Registry |
80210-62-4 |
|
| CHEBI_ID |
CHEBI:3504 |
|
| Chemical_Formula |
C15H17N5O6S2 |
|
| code |
C65305 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefpodoxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefpodoxime inhibits bacterial septum and cell wall synthesis formation. |
|
| FDA_UNII_Code |
7R4F94TVGY |
|
| FULL_SYN |
Cefpodoxime CEFPODOXIME |
|
| label |
Cefpodoxime |
|
| Legacy Concept Name |
Cefpodoxime_Base |
|
| Preferred_Name |
Cefpodoxime |
|
| prefixIRI |
Thesaurus:C65305 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0055011 |
|
| subClassOf |