loading...| Preferred Name |
Carbenicillin Disodium |
|
| Synonyms |
CARBENICILLIN DISODIUM Carbenicillin Disodium |
|
| Definitions |
The disodium salt form of carbenicillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C65285 |
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| CAS_Registry |
4800-94-6 |
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| CHEBI_ID |
CHEBI:34609 |
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| Chemical_Formula |
C17H16N2O6S.2Na |
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| code |
C65285 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The disodium salt form of carbenicillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis. |
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| FDA_UNII_Code |
9TS4B3H261 |
|
| FULL_SYN |
CARBENICILLIN DISODIUM Carbenicillin Disodium |
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Carbenicillin Disodium |
|
| Legacy Concept Name |
Carbenicillin_Disodium |
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| NSC Number |
111071 |
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| Preferred_Name |
Carbenicillin Disodium |
|
| prefixIRI |
Thesaurus:C65285 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0813202 |
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| subClassOf |