National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Methylphenidate Hydrochloride

Synonyms

Methylphenidate Hydrochloride

METHYLPHENIDATE HYDROCHLORIDE

alpha-Phenyl-2-piperidineacetic Acid Methyl Ester Hydrochloride

methylphenidate hydrochloride

Quillivant XR

Concerta

Ritalin

Definitions

The hydrochloride salt of the synthetic central nervous system stimulant methylphenidate. Methylphenidate appears to activate the brain stem arousal system and cortex to produce its stimulant effect and, in some clinical settings, may improve cognitive function.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C646

Accepted_Therapeutic_Use_For

ADHD; narcolepsy

ALT_DEFINITION

A drug used to treat certain behavior disorders, such as attention deficit hyperactivity disorder (ADHD). It is also being studied as a way to improve brain function in patients treated with anticancer drugs. Concerta acts on certain parts of the brain. It is a type of central nervous system stimulant.

CAS_Registry

298-59-9

CHEBI_ID

CHEBI:31836

Chemical_Formula

C14H19NO2.HCl

code

C646

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

The hydrochloride salt of the synthetic central nervous system stimulant methylphenidate. Methylphenidate appears to activate the brain stem arousal system and cortex to produce its stimulant effect and, in some clinical settings, may improve cognitive function.

Display_Name

Methylphenidate Hydrochloride

FDA_UNII_Code

4B3SC438HI

FULL_SYN

Methylphenidate Hydrochloride

METHYLPHENIDATE HYDROCHLORIDE

alpha-Phenyl-2-piperidineacetic Acid Methyl Ester Hydrochloride

methylphenidate hydrochloride

Quillivant XR

Concerta

Ritalin

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62045

label

Methylphenidate Hydrochloride

Legacy Concept Name

Methylphenidate

NCI_Drug_Dictionary_ID

41225

NSC Number

169868

PDQ_Closed_Trial_Search_ID

41225

PDQ_Open_Trial_Search_ID

41225

Preferred_Name

Methylphenidate Hydrochloride

prefixIRI

Thesaurus:C646

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0700545

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47795

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