loading...| Preferred Name |
Bupivacaine |
|
| Synonyms |
BUPIVACAINE bupivacaine 1-Butyl-2',6'-pipecoloxylidide Bupivacaine AH 250 |
|
| Definitions |
An amide-type, long-acting local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62011 |
|
| ALT_DEFINITION |
A drug used to relieve pain by blocking signals at nerve endings. It is being studied in the relief of pain following surgery for cancer. It is a type of local anesthetic. |
|
| CAS_Registry |
2180-92-9 38396-39-3 |
|
| CHEBI_ID |
CHEBI:3215 |
|
| Chemical_Formula |
C18H28N2O |
|
| code |
C62011 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159412 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
|
| Contributing_Source |
CPTAC CTRP FDA |
|
| DEFINITION |
An amide-type, long-acting local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation. |
|
| Display_Name |
Bupivacaine |
|
| FDA_UNII_Code |
Y8335394RO |
|
| FULL_SYN |
BUPIVACAINE bupivacaine 1-Butyl-2',6'-pipecoloxylidide Bupivacaine AH 250 |
|
| Has_Salt_Form | ||
| label |
Bupivacaine |
|
| Legacy Concept Name |
Bupivacaine_Base |
|
| NCI_Drug_Dictionary_ID |
811743 |
|
| Preferred_Name |
Bupivacaine |
|
| prefixIRI |
Thesaurus:C62011 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0006400 |
|
| subClassOf |