loading...| Preferred Name |
Penbutolol Sulfate |
|
| Synonyms |
PENBUTOLOL SULFATE Penbutolol Sulfate Levatol |
|
| Definitions |
The sulfate salt form of penbutolol, a lipophilic, nonselective beta-adrenergic receptor antagonist with anti-anginal and antihypertensive activities. Penbutolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61882 |
|
| CAS_Registry |
38363-32-5 |
|
| CHEBI_ID |
CHEBI:7955 |
|
| Chemical_Formula |
2C18H29NO2.H2SO4 |
|
| code |
C61882 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The sulfate salt form of penbutolol, a lipophilic, nonselective beta-adrenergic receptor antagonist with anti-anginal and antihypertensive activities. Penbutolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels. |
|
| FDA_UNII_Code |
US71433228 |
|
| FULL_SYN |
PENBUTOLOL SULFATE Penbutolol Sulfate Levatol |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Penbutolol Sulfate |
|
| Legacy Concept Name |
Penbutolol_Sulfate |
|
| Preferred_Name |
Penbutolol Sulfate |
|
| prefixIRI |
Thesaurus:C61882 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0282292 |
|
| subClassOf |