National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Isoflavone

Synonyms

3-phenylchromone

Soy Isoflavones

Isoflavones

ISOFLAVONE

Isoflavone

isoflavone

Definitions

A class of polyphenolic compounds derived from the Fabaceae family with potential phytoestrogenic, cholesterol-reducing, chemotherapeutic and antioxidant activity. In isoflavones the phenyl group on the benzopyran ring is in position 3 relative to the oxygen of the ring. Most isoflavones for human consumption and that are currently studied are derived from soy beans.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C599

ALT_DEFINITION

An estrogen-like substance made by some plants, including the soy plant. Soy isoflavones are being studied in the prevention of cancer, hot flashes that occur with menopause, and osteoporosis (loss of bone density).

A flavone with the phenyl group at C-3 instead of C-2.

CAS_Registry

574-12-9

CHEBI_ID

CHEBI:18220

CHEBI:38757

code

C599

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CRCH

CTRP

FDA

DEFINITION

A class of polyphenolic compounds derived from the Fabaceae family with potential phytoestrogenic, cholesterol-reducing, chemotherapeutic and antioxidant activity. In isoflavones the phenyl group on the benzopyran ring is in position 3 relative to the oxygen of the ring. Most isoflavones for human consumption and that are currently studied are derived from soy beans.

Display_Name

Isoflavone

FDA_UNII_Code

OVO2KUW8H8

FULL_SYN

3-phenylchromone

Soy Isoflavones

Isoflavones

ISOFLAVONE

Isoflavone

isoflavone

INFOODS

ISOFLVND

label

Isoflavone

Legacy Concept Name

Isoflavone

NSC Number

135405

Preferred_Name

Isoflavone

prefixIRI

Thesaurus:C599

Semantic_Type

Organic Chemical

UMLS_CUI

C0022179

Unit

mcg

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C68464

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