National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

Therapeutic Insulin
Synonyms

Therapeutic Insulin

Recombinant Insulin

INSULIN

Insulin
Definitions

A synthetic or animal-derived form of insulin used in the treatment of diabetes mellitus. Therapeutic insulin is formulated to be short-, intermediate- and long-acting in order to individualize an insulin regimen according to individual differences in glucose and insulin metabolism. Therapeutic insulin may be derived from porcine, bovine or recombinant sources. Endogenous human insulin, a pancreatic hormone composed of two polypeptide chains, is important for the normal metabolism of carbohydrates, proteins and fats and has anabolic effects on many types of tissues.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C581
ALT_DEFINITION

A synthetic or animal-derived form of insulin used in the treatment of diabetes mellitus.
CAS_Registry

11061-68-0

9004-10-8
CHEBI_ID

CHEBI:5931
code

C581
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101857

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537
Contributing_Source

CDISC

CTRP

GDC
DEFINITION

A synthetic or animal-derived form of insulin used in the treatment of diabetes mellitus. Therapeutic insulin is formulated to be short-, intermediate- and long-acting in order to individualize an insulin regimen according to individual differences in glucose and insulin metabolism. Therapeutic insulin may be derived from porcine, bovine or recombinant sources. Endogenous human insulin, a pancreatic hormone composed of two polypeptide chains, is important for the normal metabolism of carbohydrates, proteins and fats and has anabolic effects on many types of tissues.
Display_Name

Therapeutic Insulin
FULL_SYN

Therapeutic Insulin

Recombinant Insulin

INSULIN

Insulin
Has_Target

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17072
Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99532
label

Therapeutic Insulin
Legacy Concept Name

Therapeutic_Insulin
Maps_To

Insulin
NCI_Drug_Dictionary_ID

43345
NSC Number

88206
PDQ_Closed_Trial_Search_ID

43345
PDQ_Open_Trial_Search_ID

43345
Preferred_Name

Therapeutic Insulin
prefixIRI

Thesaurus:C581
Semantic_Type

Amino Acid, Peptide, or Protein

Pharmacologic Substance
UMLS_CUI

C1579433
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C548
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