National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Ethacrynic Acid

Synonyms

[2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic Acid

Ethacrynic acid

ETHACRYNIC ACID

Ethacrynic Acid

EA

Edecrin

Definitions

An unsaturated ketone derivative of aryloxyacetic acid without a sulfonamide substituent belonging to the class of loop diuretics. Ethacrynic acid is extensively bound to plasma proteins; both ethacrynic acid in its unchanged form as well as its metabolites are excreted in bile and urine.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C485

CAS_Registry

58-54-8

CHEBI_ID

CHEBI:4876

Chemical_Formula

C13H12Cl2O4

code

C485

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An unsaturated ketone derivative of aryloxyacetic acid without a sulfonamide substituent belonging to the class of loop diuretics. Ethacrynic acid is extensively bound to plasma proteins; both ethacrynic acid in its unchanged form as well as its metabolites are excreted in bile and urine.

FDA_UNII_Code

M5DP350VZV

FULL_SYN

[2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic Acid

Ethacrynic acid

ETHACRYNIC ACID

Ethacrynic Acid

EA

Edecrin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47993

label

Ethacrynic Acid

Legacy Concept Name

Ethacrynic_Acid

NCI_Drug_Dictionary_ID

41163

NSC Number

85791

PDQ_Closed_Trial_Search_ID

41163

PDQ_Open_Trial_Search_ID

41163

Preferred_Name

Ethacrynic Acid

prefixIRI

Thesaurus:C485

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0014963

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C49184

Delete Subject Author Type Created
No notes to display